Engineered probiotic-mediated intratumoral delivery and controlled release of bacterial collagenase for cancer therapy
Elevated collagen levels within breast tumors are strongly associated with tumor progression and present a barrier to effective therapeutic agent penetration within the tumor microenvironment (TME), leading to poor clinical outcomes. To address this challenge, we engineered a probiotic strain to deg...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
KeAi Communications Co., Ltd.
2025-03-01
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| Serier: | Synthetic and Systems Biotechnology |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2405805X24001200 |
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