Visualizing malignant progression: in situ CD109-based spatial immunofluorescence assay delineates papillary to anaplastic thyroid carcinoma transformation within the tumor microenvironment

Abstract Anaplastic thyroid carcinoma (ATC) is the rarest and most aggressive subtype of thyroid cancer, and considered to arise from differentiated thyroid carcinoma, however, the underlying molecular processes remain largely unknown. Using CD109 as a malignant marker, we analyzed an ATC case conta...

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מידע ביבליוגרפי

Principais autores:	Tomoko Cohen, Keiji Suzuki, Katsuya Matsuda, Hirokazu Kurohama, Yuki Matsuoka, Mayu Ueda, Shinya Satoh, Hisakazu Shindo, Hiroyuki Yamashita, Atsushi Kawakami, Masahiro Nakashima
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2026-02-01
סדרה:	Scientific Reports
נושאים:	Anaplastic thyroid cancer Spatial immunofluorescence assay CD109 Tumor microenvironment Matrix stiffening
גישה מקוונת:	https://doi.org/10.1038/s41598-026-41927-z
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!