Pharmacological Agent GW4869 Inhibits Tick-Borne Langat Virus Replication to Affect Extracellular Vesicles Secretion

GW4869, a cell-permeable, selective inhibitor of neutral sphingomyelinase is a pharmacological agent that blocks the production and release of extracellular vesicles (EVs). Our previous studies have shown that GW4869 inhibits flaviviral loads in tick, mosquito and mammalian cells, including murine c...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Md Bayzid, Biswajit Bhowmick, Waqas Ahmed, Girish Neelakanta, Hameeda Sultana
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-07-01
Цуврал:	Viruses
Нөхцлүүд:	GW4869 tick cells Langat virus EVs secretion cytotoxicity viral dilution
Онлайн хандалт:	https://www.mdpi.com/1999-4915/17/7/969
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!