CycA-Dependent Glycine Assimilation Is Connected to Novobiocin Susceptibility in Escherichia coli

ABSTRACT Escherichia coli serine hydroxymethyltransferase (GlyA) converts serine to glycine, and glyA mutants are auxotrophic for glycine. CycA is a transporter that mediates glycine uptake. Deleting glyA in E. coli strain W3110 led to activation of CysB, which was related to novobiocin (NOV) suscep...

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Bibliografische Detailangaben

Hauptverfasser:	Hongmei Shi, Ling Zhang, Jing Gu, Jinyue Li, Zixiang Liu, Jiao-Yu Deng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2022-12-01
Schriftenreihe:	Microbiology Spectrum
Schlagworte:	serine hydroxymethyltransferase threonylcarbamoyl-AMP synthase novobiocin susceptibility glycine metabolism Escherichia coli
Online-Zugang:	https://journals.asm.org/doi/10.1128/spectrum.02501-22
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