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Cost-effectiveness analysis of first-line versus second-line use of CDK4/6 inhibitors combined with endocrine therapy in advanced HR+/HER2- breast cancer in China: based on the SONIA trial

BackgroundThe optimal sequencing of CDK4/6 inhibitors combined with endocrine therapy for advanced hormone receptor-positive, HER2-negative (HR+/HER2-) breast cancer remains uncertain, particularly in resource-limited settings such as China. This study evaluated the cost-effectiveness of first-line...

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Principais autores: Xiaohu Jin, Zhifeng Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Pharmacology
Fag:
cost-effectiveness analysis
CDK4/6 inhibitors
endocrine therapy
HR+/HER2- breast cancer
SONIA
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2025.1700291/full
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