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Cardiac HDAC3 Disruption Contributes to HDAC Inhibitor-Induced QT Prolongation

Histone deacetylase (HDAC) inhibitors are approved for cancer treatment and are being investigated for a wide range of other diseases. Despite their therapeutic promise, clinical studies have reported cardiac side effects, particularly electrocardiogram (EKG) abnormalities, with QT interval prolonga...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jiao Lu, Christopher Ward, Sichong Qian, Lilei Zhang, Jiang Chang, Zheng Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-05-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/15/10/902
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