Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations
Mutations in ATP-binding cassette A3 (ABCA3), a phospholipid transporter critical for surfactant homeostasis in pulmonary alveolar type II epithelial cells (AEC2s), are the most common genetic causes of childhood interstitial lung disease (chILD). Treatments for patients with pathological variants o...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
American Society for Clinical Investigation
2024-01-01
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| Rangatū: | The Journal of Clinical Investigation |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1172/JCI164274 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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