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Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats

Abstract Background Traumatic brain injury (TBI) is one of the major causes of mortality and disability for all ages worldwide. Mesenchymal stem cells (MSCs)-originated exosomes have provided therapeutic effects. However, as an indispensable component of MSCs, whether odontogenic stem cell-generated...

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Principais autores: Ye Li, Yuan-Yuan Yang, Jia-Li Ren, Feng Xu, Fa-Ming Chen, Ang Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-09-01
Serier:Stem Cell Research & Therapy
Fag:
Traumatic brain injury
Stem cells from human exfoliated deciduous teeth
Exosomes
Microglia
Neuroinflammation
Online adgang:http://link.springer.com/article/10.1186/s13287-017-0648-5
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