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Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses

Abstract Background The tumor-derived GL261 cell line is used as a model for studying glioblastoma and other high-grade gliomas, and can be cultured adherently or as free-floating aggregates known as neurospheres. These different culture conditions give rise to distinct phenotypes, with increased tu...

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Hlavní autoři: Averey D. Strong, Richard L. Daniels
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2017-08-01
Edice:BMC Cancer
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On-line přístup:http://link.springer.com/article/10.1186/s12885-017-3507-y
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