Computational-guided discovery of UDP-glycosyltransferases for lauryl glucoside production using engineered E. coli

Abstract Defining suitable enzymes for reaction steps in novel synthetic pathways is crucial for developing microbial cell factories for non-natural products. Here, we developed a computational workflow to identify C12 alcohol-active UDP-glycosyltransferases. The workflow involved three steps: (1) a...

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Prif Awduron:	Kasimaporn Promubon, Kritsada Tathiya, Aussara Panya, Wasu Pathom-Aree, Pachara Sattayawat
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	SpringerOpen 2024-10-01
Cyfres:	Bioresources and Bioprocessing
Pynciau:	UDP-glycosyltransferase Lauryl glucoside Computational method 1-Dodecanol Engineered E. coli Novel biosynthetic pathway
Mynediad Ar-lein:	https://doi.org/10.1186/s40643-024-00820-1
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!