Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells

In gray matter pathology of multiple sclerosis, neurodegeneration associates with a high degree of meningeal inflammatory activity. Importantly, ectopic lymphoid follicles (eLFs) were identified at the inflamed meninges of patients with progressive multiple sclerosis. Besides T lymphocytes, they com...

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Hlavní autoři:	Luisa Bell, Alexander Lenhart, Andreas Rosenwald, Camelia M. Monoranu, Friederike Berberich-Siebelt
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-01-01
Edice:	Frontiers in Immunology
Témata:	ectopic lymphoid follicle lymphoid aggregate T-follicular regulatory cell meningeal inflammation NFATc1 progressive multiple sclerosis
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2019.03090/full
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