Código QR

Engineered circular guide RNAs boost CRISPR/Cas12a- and CRISPR/Cas13d-based DNA and RNA editing

Abstract Background The CRISPR/Cas12a and CRISPR/Cas13d systems are widely used for fundamental research and hold great potential for future clinical applications. However, the short half-life of guide RNAs (gRNAs), particularly free gRNAs without Cas nuclease binding, limits their editing efficienc...

ver descrição completa

Na minha lista:
Principais autores: Xin Zhang, Xinlong Wang, Jie Lv, Hongxin Huang, Jiahong Wang, Ma Zhuo, Zhihong Tan, Guanjie Huang, Jiawei Liu, Yuchen Liu, Mengrao Li, Qixiao Lin, Lian Li, Shufeng Ma, Tao Huang, Ying Lin, Xiaoyang Zhao, Zhili Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-06-01
Colecção:Genome Biology
Assuntos:
cgRNA
Engineered circular gRNA
Cas12a
Cas13d
Gene activation
DNA editing
Acesso em linha:https://doi.org/10.1186/s13059-023-02992-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados