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SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres

SLX4 interacts with several endonucleases to resolve structural barriers in DNA metabolism. SLX4 also interacts with telomeric protein TRF2 in human cells. The molecular mechanism of these interactions at telomeres remains unknown. Here, we report the crystal structure of the TRF2-binding motif of S...

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Principais autores: Bingbing Wan, Jinhu Yin, Kent Horvath, Jaya Sarkar, Yong Chen, Jian Wu, Ke Wan, Jian Lu, Peili Gu, Eun Young Yu, Neal F. Lue, Sandy Chang, Yie Liu, Ming Lei
格式: Artigo
語言:Inglês
出版: Elsevier 2013-09-01
叢編:Cell Reports
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211124713004580
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