Case report: JAK1/2 inhibition with baricitinib in the treatment of STING-associated vasculopathy with onset in infancy

Abstract Background Gain-of-function mutations in STING1 (also known as TMEM173) which result in constitutive activation of STING, have been reported to cause STING-associated vasculopathy with onset in infancy (SAVI). Although a wider spectrum of associated manifestations and perturbations in disea...

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Detalhes bibliográficos

Principais autores:	Jianqiang Wu, Qing Zhou, Hua Zhou, Meiping Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
Colecção:	Pediatric Rheumatology Online Journal
Assuntos:	STING-associated vasculopathy with onset in infancy (SAVI) Type I interferonopathy Janus kinase inhibitors (JAK inhibitors) Interstitial lung Disease (ILD)
Acesso em linha:	https://doi.org/10.1186/s12969-023-00916-6
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