PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast

Abstract SUMOylation, a conserved post-translational modification in eukaryotes, regulates protein function, localization, and stability. However, the role of SUMO chains in genome maintenance is still emerging. Using Schizosaccharomyces pombe, we show that loss of SUMO chains results in spontaneous...

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Autores principales:	Katarzyna Markowska, Ireneusz Litwin, Dorota Misiorna, Julia Kończak, Aleksandra Bogdańska, Paulina Tomaszewska, Michał Tracz, Mika Haenen, Karol Kramarz
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-12-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-025-65862-1
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