Synthesis and Cytotoxic Activity of the Derivatives of <i>N</i>-(Purin-6-yl)aminopolymethylene Carboxylic Acids and Related Compounds

Testing a number of <i>N</i>-[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2<i>H</i>-[1,4]benzoxazine in a panel of nine tumor cell lines has shown that the studied compounds exhibit high cytotoxic activity, especially against 4T1 murine mammary carcinoma, COLO20...

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Главные авторы:	Victor P. Krasnov, Olga A. Vozdvizhenskaya, Maria A. Baryshnikova, Alexandra G. Pershina, Vera V. Musiyak, Tatyana V. Matveeva, Kseniya V. Nevskaya, Olga Y. Brikunova, Dmitry A. Gruzdev, Galina L. Levit
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2023-02-01
Серии:	Molecules
Предметы:	purine omega-amino acids 7,8-difluoro-3,4-dihydro-3-methyl-2<i>H</i>-[1,4]benzoxazine cytotoxicity tumor cells
Online-ссылка:	https://www.mdpi.com/1420-3049/28/4/1853
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