Slowly expanding lesions relate to persisting black-holes and clinical outcomes in relapse-onset multiple sclerosis

Background: Slowly expanding lesions (SELs) are MRI markers of chronic active lesions in multiple sclerosis (MS). T1-hypointense black holes, and reductions in magnetization transfer ratio (MTR) are pathologically correlated with myelin and axonal loss. While all associated with progressive MS, the...

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Autors principals:	Alberto Calvi, Carmen Tur, Declan Chard, Jonathan Stutters, Olga Ciccarelli, Rosa Cortese, Marco Battaglini, Anna Pietroboni, Milena De Riz, Daniela Galimberti, Elio Scarpini, Nicola De Stefano, Ferran Prados, Frederik Barkhof
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-01-01
Col·lecció:	NeuroImage: Clinical
Matèries:	Chronic active lesions SEL Black holes Volumetric MRI Multiple sclerosis
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2213158222001139
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