An in silico procedure for generating protein-mediated chromatin interaction data and comparison of significant interaction calling methods.
The ability to simulate high-throughput data with high fidelity to real experimental data is fundamental for benchmarking methods used to detect true long-range chromatin interactions mediated by a specific protein. Yet, such tools are not currently available. To fill this gap, we develop an in sili...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Acceso en liña: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287521&type=printable |
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