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TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques

Abstract Rupture of unstable atherosclerotic plaques is a major cause of mortality. Endothelial-to-mesenchymal transition associates with advanced atherosclerotic plaques and contributes to plaque progression. We examined the role of Twist1, a transcription factor that drives endothelial-to-mesenchy...

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Hlavní autoři: Blanca Tardajos Ayllon, Mannekomba Diagbouga, Ankita Das, Siyu Tian, Andreas Edsfeldt, Joanna Kalucka, Jovana Serbanovic-Canic, Emily Chambers, Jiangming Sun, Chrysostomi Gialeli, Mark Dunning, Sheila E. Francis, Xiuying Li, Akiko Mammoto, Michael Simons, Helle F. Jørgensen, Isabel Goncalves, Suowen Xu, Paul C. Evans
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-02-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-026-69808-z
Tagy: Přidat tag
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