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Promoters maintain their relative activity levels under different growth conditions

Abstract Most genes change expression levels across conditions, but it is unclear which of these changes represents specific regulation and what determines their quantitative degree. Here, we accurately measured activities of ∼900 S. cerevisiae and ∼1800 E. coli promoters using fluorescent reporters...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Leeat Keren, Ora Zackay, Maya Lotan‐Pompan, Uri Barenholz, Erez Dekel, Vered Sasson, Guy Aidelberg, Anat Bren, Danny Zeevi, Adina Weinberger, Uri Alon, Ron Milo, Eran Segal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature 2013-10-01
Schriftenreihe:Molecular Systems Biology
Schlagworte:
gene expression
growth rate
modeling
promoter activity
transcription regulation
Online-Zugang:https://doi.org/10.1038/msb.2013.59
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