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Oviduct-specific expression of human neutrophil defensin 4 in lentivirally generated transgenic chickens.

The expression of oviduct-specific recombinant proteins in transgenic chickens is a promising technology for the production of therapeutic biologics in eggs. In this study, we constructed a lentiviral vector encoding an expression cassette for human neutrophil defensin 4 (HNP4), a compound that disp...

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Autors principals: Tongxin Liu, Hanyu Wu, Dainan Cao, Qingyuan Li, Yaqiong Zhang, Ning Li, Xiaoxiang Hu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4447378?pdf=render
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