Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice
Treatment of pain with morphine and its congeners in sickle cell anemia is suboptimal, warranting the need for analgesics devoid of side effects, addiction and tolerance liability. Small-molecule nociceptin opioid receptor ligands show analgesic efficacy in acute and chronic pain models. We show tha...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2015-12-01
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| Colecção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/7579 |
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