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Investigation of fingolimod-induced lymphocyte sequestration on inflammatory response and neurological damages after cardiac arrest

Abstract Background A sepsis-like syndrome is known to occur after cardiac arrest, leading to cerebral infiltration by white blood cells (WBC). We hypothesized that pharmacological sequestration of WBC, and more specifically lymphocytes within lymphoid tissues, could reduce the cerebral infiltration...

Celý popis

Uloženo v:
Hlavní autoři: Yara Abi Zeid Daou, Fanny Lidouren, Antoine Bois, Naoto Watanabe, Ali Jendoubi, Estelle Faucher, Mathieu Surenaud, Sophie Chateau-Joubert, Sophie Hue, Bijan Ghaleh, Matthias Kohlhauer, Renaud Tissier
Médium: Artigo
Jazyk:Inglês
Vydáno: SpringerOpen 2024-07-01
Edice:Intensive Care Medicine Experimental
Témata:
Cardiac arrest
Resuscitation
Lymphocyte
Sepsis-like
Inflammation
Neurological dysfunction
On-line přístup:https://doi.org/10.1186/s40635-024-00645-4
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