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Caspase-3 activation and increased procollagen type I in irradiated hearts

The caspase-3-cleaved presence was evaluated in this study in the heart of irradiated rats, during the decline of ventricular function. Female Wistar rats were irradiated with a single dose of radiation (15 Gy) delivered directly to the heart and the molecular, histological and physiological evaluat...

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Автори: Samara C. Ferreira-Machado, Camila Salata, Nazareth N. Rocha, Alexandre F.S. Corrêa, Suzana Côrte-Real, Antônio A.F. Peregrino, Vera M.A. de Campos, Cherley B.V. Andrade, Mario Bernardo-Filho, Januário B. Cabral-Neto, Carlos E. Dealmeida
Формат: Artigo
Мова:Inglês
Опубліковано: Academia Brasileira de Ciências 2013-03-01
Серія:Anais da Academia Brasileira de Ciências
Предмети:
apoptose
caspase-3
fibrose
coração
radiação ionizante
TGF-β1
Онлайн доступ:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100215&lng=en&tlng=en
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