The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells

Abstract Homer is a postsynaptic scaffold protein, which has long and short isoforms. The long form of Homer consists of an N-terminal target-binding domain and a C-terminal multimerization domain, linking multiple proteins within a complex. The short form of Homer only has the N-terminal domain and...

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Hlavní autoři:	Teiichi Furuichi, Yuko Muto, Tetsushi Sadakata, Yumi Sato, Kanehiro Hayashi, Yoko Shiraishi-Yamaguchi, Yo Shinoda
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-06-01
Edice:	Molecular Brain
Témata:	Homer2 Cerebellar granule cell NMDAR Excitotoxicity
On-line přístup:	https://doi.org/10.1186/s13041-021-00804-8
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