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Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles

Abstract Early-life adversity covers a range of physical, social and environmental stressors. Acute viral infections in early life are a major source of such adversity and have been associated with a broad spectrum of later-life effects outside the immune system or “off-target”. These include an alt...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Myriam P. Merz, Snehaa V. Seal, Nathalie Grova, Sophie Mériaux, Pauline Guebels, Georgia Kanli, Elise Mommaerts, Nathalie Nicot, Tony Kaoma, Olivier Keunen, Petr V. Nazarov, Jonathan D. Turner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-03-01
Schriftenreihe:Scientific Reports
Schlagworte:
Early life adversity
Infection
HPA axis
Stress
Corticosterone
Gluconeogenesis
Online-Zugang:https://doi.org/10.1038/s41598-024-56601-5
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