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5' long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals

<p>Abstract</p> <p>We previously described selective hypermethylation of the 5'-long terminal repeat (LTR) of HTLV-1 provirus <it>in vivo </it>and <it>in vitro</it>. This prompted us to analyze CpG methylation of the two LTRs of the HIV provirus in chronically infected cell lines. The results demons...

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Autori principali: Watanabe Toshiki, Koiwa Tsukasa, Hamano Akiko, Ishida Takaomi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2006-10-01
Serie:Retrovirology
Accesso online:http://www.retrovirology.com/content/3/1/69
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