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Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis

Cryptosporidium infection can cause severe diarrhea with limited treatment options available. Here, Lunde et al. perform a drug repositioning screen with a library of benzoxaboroles and identify AN7973 as potent inhibitor of intracellular parasite development with good efficacy in murine and neonata...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Christopher S. Lunde, Erin E. Stebbins, Rajiv S. Jumani, Md Mahmudul Hasan, Peter Miller, John Barlow, Yvonne R. Freund, Pamela Berry, Rianna Stefanakis, Jiri Gut, Philip J. Rosenthal, Melissa S. Love, Case W. McNamara, Eric Easom, Jacob J. Plattner, Robert T. Jacobs, Christopher D. Huston
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2019-06-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-019-10687-y
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