PERK and filamin A in actin cytoskeleton remodeling at ER-plasma membrane contact sites
The endoplasmic reticulum (ER) stress sensor protein kinase RNA-like endoplasmic reticulum kinase (PERK) plays a major role during the unfolded protein response (UPR), mainly through eIF2α phosphorylation. We uncovered that PERK, by interacting with Filamin A, elicits F-actin remodeling required for...
Guardado en:
| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis Group
2017-09-01
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| Colección: | Molecular & Cellular Oncology |
| Materias: | |
| Acceso en línea: | http://dx.doi.org/10.1080/23723556.2017.1340105 |
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