Comparative In Vitro Evaluation of Anti-HIV Immunotoxin, Antibody–Drug Conjugate, and Radioimmunoconjugate Targeted by the Same Antibody

Background: We are developing cytotoxic immunoconjugates (CICs) to eliminate HIV-infected cells. We investigated the efficacy and kinetics of killing by different forms of CICs targeted by the same monoclonal antibody (mAb), an immunotoxin (IT), antibody-drug conjugate (ADC), and radioimmunoconjugat...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Anne-Sophie Kuhlmann, Tami Peters, Donald K. Hamlin, Yawen Li, Xinyi Wang, Megan Stackhouse, Frances M. Cole, Jasmin Martinez-Reyes, Brenda M. Sandmaier, Hans-Peter Kiem, D. Scott Wilbur, Robert D. Harrington, Seth H. Pincus
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-01-01
coleção:	Antibodies
Assuntos:	HIV reservoir eradication monoclonal antibody cytotoxic immunoconjugate antibody-drug conjugate immunotoxin radioimmunoconjugate
Acesso em linha:	https://www.mdpi.com/2073-4468/15/1/12
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!