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Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma

T cell-engaging therapies involving bispecific T cell engager (BiTE) and chimeric antigen receptor T (CAR-T) cells have achieved great success in the treatment of hematological tumors. However, the paucity of ideal cell surface molecules that can be targeted on glioblastoma (GBM) partially reduces t...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Gaowei Li, Zongliang Zhang, Linjun Cai, Xin Tang, Jianhan Huang, Lingyu Yu, Guoqing Wang, Kunhong Zhong, Yi Cao, Chang Liu, Yuelong Wang, Aiping Tong, Liangxue Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2021-01-01
Schriftenreihe:OncoImmunology
Schlagworte:
Online-Zugang:http://dx.doi.org/10.1080/2162402X.2021.1983306
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