Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants’ Full-Length Spikes in a Multiplex Luminex Assay

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to evolve, with mutations leading to the emergence of new variants. JN.1, a subvariant of omicron BA.2.86, has demonstrated marked immune escape and is now included in updated vaccine formulations. While reduced sensitivity has b...

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Автори:	Gerald Waweru, Ruth Nyakundi, Bernadette Kutima, Sharon Owuor, Gloria Konyino, John Gitonga, Doreen Lugano, Angela Maina, Jennifer Musyoki, Lucy Ochola, Martin Omondi, Christopher K. Kariuki, Paul Ogongo, Christina Mwachari, Faiz Shee, Charles Agoti, Charles Sande, Sophie Uyoga, Eunice Kagucia, Ambrose Agweyu, Philip Bejon, J. Anthony G. Scott, George M. Warimwe, L. Isabella Ochola-Oyier, James Nyagwange
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2025-09-01
Серія:	Viruses
Предмети:	SARS-CoV-2 wildtype omicron ELISA Luminex sensitivity
Онлайн доступ:	https://www.mdpi.com/1999-4915/17/9/1248
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