Impaired mucosal IgA response to SARS-CoV-2 in patients with inborn errors of immunity

BackgroundPatients with inborn errors of immunity (IEI) often exhibit impaired responses to vaccination and infection, yet their systemic and mucosal antibody dynamics against SARS-CoV-2 remain incompletely understood.MethodsWe investigated humoral immunity in 93 IEI patients recruited during the ea...

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Autori principali:	Fanglei Zuo, Samaneh Delavari, Sima Shokri, Yating Wang, Farhad Abolnezhadian, Sara Iranparast, Fereshte Salami, Samin Sharafian, Zahra Chavoshzadeh, Nima Rezaei, Hassan Abolhassani
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-03-01
Serie:	Frontiers in Immunology
Soggetti:	breakthrough infection inborn errors of immunity mucosal immunity primary antibody deficiency SARS-CoV-2
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1696834/full
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