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Integrative single-cell analysis reveals endothelial diversity in the vasa vasorum of human atherosclerosis

Abstract Microvessels within atherosclerotic plaques are crucially involved in disease progression. Here, we generated a transcriptomic atlas of human atherosclerosis at single-cell resolution, encompassing 17,367 vascular endothelial cells (VECs) from five scRNA-seq studies, and verified key morpho...

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Hlavní autoři: Yanzhao Wu, Zhiwei Xue, Tao Sun, Yinda Yu, Xiangjun Liang, Wenchen Xing, Feiyu Mu, Zhihan Zhang, Meilin Lv, Lu Ling, Mengtao Han, Lian Cheng, Anton Gisterå, Donghai Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-04-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-026-10095-1
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