Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation

Human cytomegalovirus (HCMV) is a prototypical β-herpesvirus which frequently causes morbidity and mortality in individuals with immature, suppressed, or senescent immunity. HCMV is sensed by various pattern recognition receptors, leading to the secretion of pro-inflammatory cytokines including tumo...

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Bibliografiske detaljer

Principais autores:	Vu Thuy Khanh Le-Trilling, Fabienne Maaßen, Benjamin Katschinski, Hartmut Hengel, Mirko Trilling
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2023-08-01
Serier:	Frontiers in Immunology
Fag:	human cytomegalovirus (hcmv) tumor necrosis factor alpha (TNFα) TNF receptor 1 (TNFR1) TNF receptor 2 (TNFR2) ULb’ UL148
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1170300/full
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