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Dexborneol Amplifies Pregabalin’s Analgesic Effect in Mouse Models of Peripheral Nerve Injury and Incisional Pain

Pregabalin is a medication primarily used in the treatment of neuropathic pain and anxiety disorders, owing to its gabapentinoid properties. Pregabalin monotherapy faces limitations due to its variable efficacy and dose-dependent adverse reactions. In this study, we conducted a comprehensive investi...

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Principais autores: Zhen Shen, Yun-Dan Guo, Ming-Ze Tang, Ping Zhou, Yu-Xin Su, Hao-Ran Shen, Tao Li, Wei Jiang, Yan-Xing Han, Cai Tie, Jing-Jing Cui, Tian-Le Gao, Jian-Dong Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-07-01
coleção:Antioxidants
Assuntos:
chronic pain
combination therapy
neuroinflammation
HMGB1
ATP
Nrf2
Acesso em linha:https://www.mdpi.com/2076-3921/13/7/803
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