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Chromoanagenesis in Osteosarcoma

Chromoanagenesis is a catastrophic genomic phenomenon involving sudden, extensive rearrangements within one or a few cell cycles. In osteosarcoma, the most prevalent malignant bone tumor in children and adolescents, these events dramatically alter the genomic landscape, frequently disrupting key tum...

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Furkejuvvon:
Váldodahkkit: Guozhuang Li, Nan Wu, Jen Ghabrial, Victoria Stinnett, Melanie Klausner, Laura Morsberger, Patty Long, Ezra Baraban, John M. Gross, Ying S. Zou
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2025-06-01
Ráidu:Biomolecules
Fáttát:
chromoanagenesis
osteosarcoma
structural variant
chromothripsis
chromoanasynthesis
copy number variant
Liŋkkat:https://www.mdpi.com/2218-273X/15/6/833
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