Functional Expression and Regulation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels (HCN) in Mouse iPS Cell-derived Cardiomyocytes after UTF1-Neo Selection

Background/Aims: In vitro reprogramming of somatic cells holds great potential to serve as an autologous source of cells for tissue repair. However, major difficulties in achieving this potential include obtaining homogeneous and stable cells for transplantation. High electrical activity of cells su...

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Bibliographic Details

Main Authors:	Judith Semmler, Martin Lehmann, Kurt Pfannkuche, Michael Reppel, Jürgen Hescheler, Filomain Nguemo
Format:	Artigo
Language:	Inglês
Published:	Cell Physiol Biochem Press GmbH & Co KG 2014-09-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Cardiomyocytes Heart development Induced pluripotent stem cells Hyperpolarization-activated cation channel Whole-cell patch-clamp
Online Access:	http://www.karger.com/Article/FullText/366332
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