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Hypoxic stress and hypoxia-inducible factors in leukemias

To cope with hypoxic stress, ancient organisms have developed evolutionally conserved programs centered on hypoxia-inducible transcriptional factors (HIFs). HIFs and their regulatory proteins have evolved as rheostats to adapt cellular metabolism to atmospheric oxygen fluctuations, but the amplitude...

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Bibliografiske detaljer
Principais autores: Daniela Magliulo, Rosa Bernardi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-08-01
Serier:Frontiers in Oncology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2022.973978/full
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