Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3

Signal transducer and activator of transcription 3 (STAT3) is an attractive therapeutic target for cancer treatment. In this study, we identify lycorine is an effective inhibitor of STAT3, leading to repression of multiple oncogenic processes in colon carcinoma. Lycorine selectively inactivates phos...

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Autors principals:	Song Wu, Yuling Qiu, Yingying Shao, Shuangshuang Yin, Rui Wang, Xu Pang, Junhong Ma, Chunze Zhang, Bo Wu, Sangho Koo, Lifeng Han, Yi Zhang, Xiumei Gao, Tao Wang, Haiyang Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2018-08-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	lycorine STAT3 target apoptosis colorectal cancers
Accés en línia:	https://www.frontiersin.org/article/10.3389/fphar.2018.00881/full
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