IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course...

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Autores principales:	Ashmita Tontanahal, Vanessa Sperandio, Olga Kovbasnjuk, Sebastian Loos, Ann-Charlotte Kristoffersson, Diana Karpman, Ida Arvidsson
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2022-02-01
Colección:	Frontiers in Immunology
Materias:	Escherichia coli O157:H7 Shiga toxin EspP immunoglobulin G hemolytic uremic syndrome mouse
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.807959/full
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