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A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo

Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding capillary network often lead to transplantation failure. Herein, a novel bioartificial pancreas is constructed via islet...

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Principais autores: Haofei Li, Yulian Shang, Qi Feng, Yang Liu, Junlin Chen, Hua Dong
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2023-09-01
Serier:Bioactive Materials
Fag:
Type 1 diabetes
Bioartificial pancreas
Islet encapsulation
Core-shell microgel
Prevascularized scaffold
Online adgang:http://www.sciencedirect.com/science/article/pii/S2452199X23001299
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