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Pathogenesis of peritoneal high‐grade serous carcinoma after risk‐reducing surgery: a systematic review

Abstract Germline BRCA1/2 pathogenic variant carriers have an increased risk for high‐grade serous carcinoma (HGSC) and are therefore advised to have risk‐reducing salpingo‐oophorectomy around the age of 40. However, a risk of 0.9% to develop peritoneal HGSC remains in these women, which increases t...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Tamar A Gootzen, Anouk B Bouwmeester, Joanne A deHullu, Jurgen MJ Piek, Jeroen AWM van derLaak, Michiel Simons, Miranda P Steenbeek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2025-07-01
Schriftenreihe:The Journal of Pathology: Clinical Research
Schlagworte:
peritoneal carcinomatosis
ovarian cancer
salpingectomy
pathophysiology
Online-Zugang:https://doi.org/10.1002/2056-4538.70037
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