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SP-A binds alpha<sub>1</sub>-antitrypsin <it>in vitro </it>and reduces the association rate constant for neutrophil elastase

<p>Abstract</p> <p>Background</p> <p>α1-antitrypsin and surfactant protein-A (SP-A) are major lung defense proteins. With the hypothesis that SP-A could bind α1-antitrypsin, we designed a series of <it>in vitro </it>experiments aimed at investigating the nature and consequences of such an interactio...

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Bibliografische Detailangaben
Hauptverfasser: Carrabino Natalia, Dalzoppo Daniele, Rognoni Paola, Santos Conceição, Iadarola Paolo, Lupi Anna, Gorrini Marina, Pozzi Ernesto, Baritussio Aldo, Luisetti Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2005-12-01
Schriftenreihe:Respiratory Research
Online-Zugang:http://respiratory-research.com/content/6/1/146
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