A predictable conserved DNA base composition signature defines human core DNA replication origins
In metazoan the DNA sequence elements characterizing origin specification are unknown. By generating and analysing 19 SNS-seq datasets from different human cell types, the authors reveal a class and features of Core origins of replication which can be predicted by an algorithm.
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| Principais autores: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2020-09-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-020-18527-0 |
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