Using the LN34 Pan-Lyssavirus Real-Time RT-PCR Assay for Rabies Diagnosis and Rapid Genetic Typing from Formalin-Fixed Human Brain Tissue

Human rabies post mortem diagnostic samples are often preserved in formalin. While immunohistochemistry (IHC) has been routinely used for rabies antigen detection in formalin-fixed tissue, the formalin fixation process causes nucleic acid fragmentation that may affect PCR amplification. This study r...

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Autores principales:	Rene Edgar Condori, Michael Niezgoda, Griselda Lopez, Carmen Acosta Matos, Elinna Diaz Mateo, Crystal Gigante, Claire Hartloge, Altagracia Pereira Filpo, Joseph Haim, Panayampalli Subbian Satheshkumar, Brett Petersen, Ryan Wallace, Victoria Olson, Yu Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2020-01-01
Colección:	Viruses
Materias:	rabies virus lyssavirus diagnosis ln34 assay formalin-fixed tissue genetic typing
Acceso en línea:	https://www.mdpi.com/1999-4915/12/1/120
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