HLA-DR-DQ associations, combined with PLASMIC score, are reliable predictors of acquired thrombotic thrombocytopenic purpura (aTTP) and aid in differentiating aTTP from other thrombotic microangiopathies

Background: Thrombotic microangiopathies (TMA) are a group of disorders with overlapping clinical features that require urgent intervention. Treatment is based on the recognition of the TMA type, which is often challenging. The aim of this study was to identify specific HLA associations with differe...

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Principais autores:	Soumya Pandey, Akul Shrivastava, Yanping Izak Harville, Michele Cottler-Fox, Terry O. Harville
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-11-01
Colecção:	Hematology, Transfusion and Cell Therapy
Assuntos:	Thrombotic microangiopathies HLA associations PLASMIC score PPV and NPV
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2531137924000129
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