7-GTDF from Archidendron clypearia extract inhibits PRRSV entry and interacts with the CD163 receptor

Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) poses a major threat to global swine production, with no clinically approved specific therapeutics. Archidendron clypearia (AC), a medicinal plant traditionally used for human upper respiratory infections, exhibits broad...

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Autores principales:	Jing Yang, Xiaoli Zhang, Hao Wu, Wei Peng, Weiwei Su, Peibo Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2026-05-01
Colección:	BMC Veterinary Research
Materias:	PRRSV Archidendron clypearia Antiviral activity 7-O-galloyltricetiflavan CD163 receptor TLR4-NF-κB signaling pathway
Acceso en línea:	https://doi.org/10.1186/s12917-026-05489-6
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