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SUV39 SET domains mediate crosstalk of heterochromatic histone marks

The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly understood. Clr4 is the sole H3K9me2/3 methyltrans...

Deskribapen osoa

Gorde:
Egile Nagusiak: Alessandro Stirpe, Nora Guidotti, Sarah J Northall, Sinan Kilic, Alexandre Hainard, Oscar Vadas, Beat Fierz, Thomas Schalch
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications Ltd 2021-09-01
Saila:eLife
Gaiak:
heterochromatin
methyltransferase
ubiquitin
posttranslational modifications
enzyme kinetics
protein complex
Sarrera elektronikoa:https://elifesciences.org/articles/62682
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