Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework

Summary: The scPrediXcan framework enables cell-type-specific transcriptome-wide association studies (TWASs) by integrating deep learning-based prediction of gene expression from DNA sequence and epigenetic features. We present a protocol for scPrediXcan: training cell-type-specific models for expre...

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Auteurs principaux:	Yichao Zhou, Sarah Sumner, Temidayo Adeluwa, Lisha Zhu, Sofia Salazar-Magaña, Hyunki Kim, Saideep Gona, Festus Nyasimi, Rohit Kulkarni, Joseph Powell, Ravi Madduri, Boxiang Liu, Mengjie Chen, Hae Kyung Im
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2026-03-01
Collection:	STAR Protocols
Sujets:	Bioinformatics sequence analysis Genetics genomics gene expression
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2666166725007129
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